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Bodybuilding and most other workout regimens aim to increase lean muscle mass while reducing body fat, but many people will use a combination of exercise and food, often with varying levels of success. "There are times you can't exercise or eat what you want just to find enough fat loss," explained Mark Sisson, a physician who specializes in the treatment of the metabolic syndrome. In general, if you're losing weight, eat more than if you're gaining weight, he said. Some people will use food to achieve those results and not exercise at all. The problem is that this can be a dangerous approach — "eating enough when you gain a lot of fat may lead to eating more than you need," Sisson added. That has been borne out by a number of trials, including a 2014 study, published in the Journal of the American Medical Association, that found eating three to five large meals a day to replace each additional calorie you burn may not be sustainable long term. The study examined the impact of restricting fat intake on body mass and body fat percentage in overweight individuals who followed a low-fat diet for six months. The results showed a significant increase in weight compared with the control group, even when both calories burned and body mass were reduced. So, what should you do? The conventional approach — keeping calories the same or eating more often — will do your body good when it's getting leaner, but a diet that's low in calories and is high in fat can wreak havoc in the long term. "A combination of the two is the most sustainable long-term approach," said Lyle McDonald, an associate professor of clinical nutrition at the University of Miami Miller School of Medicine. In a 2015 clinical trial, Dr. McDonald led a study of 18 adults who lost 11 pounds by following a low-fat, fat-free diet between November 2013 and April 2014. All of the participants lost a significant amount of weight; the control group lost about 4.5 pounds less. But there were more than two-thirds of the participants in the control group who showed signs of being overweight when they returned to their normal weight the next year. "This is a well-known, well-documented effect of the Mediterranean diet, low-fat diet and calorie restriction," Dr. McDonald said in an interview. "So what does have less attention are the metabolic disorders that these patients had." He emphasized that he does not advocate a diet that's as restrictive as that recommended by the American Heart Association. "The Mediterranean diet is very Similar articles: